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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Ulnar-Mammary Syndrome (UMS) approved 181450
UNC13A related neuromuscular disorder approved *609894
Usher Syndrome Type 1 (USH1) approved 276900
Usher Syndrome, Type IB (USH1B) approved 276900
Usher Syndrome, Type IC (USH1C) approved 276904
Usher Syndrome, Type ID (USH1D) approved 601067
Usher Syndrome, Type IF (USH1F) approved 602083
Usher Syndrome, Type IG (USH1G) approved 606943
Usher Syndrome, Type IIA (USH2A) approved 276901
Usher Syndrome, Type IIC (USH2C) approved 605472
Usher Syndrome, Type IID (USH2D) approved 611383
Usher Syndrome, Type IJ (USH1J) approved 614869
Van Der Woude Syndrome 1 (VWS1) approved 119300
Van Esch-O'Driscoll Syndrome (VEODS) approved 301030
Vasculopathy, Retinal, with Cerebral Leukoencephalopathy and Systemic Manifestations (RVCLS) approved 192315
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, with or without Atrial Dysfunction and/or Dilated Cardiomyopathy (CPVT1) approved 604772
Ventricular Tachycardia, Catecholaminergic Polymorphic, 2 (CPVT2) approved 611938
Ventricular Tachycardia, Catecholaminergic Polymorphic, 3 (CPVT3) approved 614021
Ventricular Tachycardia, Catecholaminergic Polymorphic, 4 (CPVT4) approved 614916
Ventriculomegaly with Cystic Kidney Disease (VMCKD) approved 219730