Skip to main content

You have chosen not to allow videos from the 3rd party streaming service (YouTube), if you would like to see these videos, please change your Privacy policy and cookie settings.

The HFEA has launched its new data dashboard with data going back over 30 years. Access it here.

PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Myotubular myopathy approved 310400, 300219
Nail-Patella Syndrome (NPS) approved 161200
Nance-Horan Syndrome (NHS) approved 302350
Naxos Disease (NXD) approved 601214
Nemaline Myopathy ACTA 1 approved 161800
Nemaline myopathy type 2 (NEM2) approved 256030
Nemaline Myopathy type 8 approved 615348
Neonatal Inflammatory Skin and Bowel Disease 1 (NISBD1) approved 614328
Neonatal Inflammatory Skin and Bowel Disease 2 (NISBD2) approved 616069
Nephrogenic Diabetes Insipidus (NDI) approved 304800
Nephronophthisis 1, (NPHP1) approved 256100
Nephronophthisis 11, (NPHP11) approved 613550
Nephronophthisis 12, (NPHP12) approved 613820
Nephronophthisis 13, (NPHP13) approved 614377
Nephronophthisis 14, (NPHP14) approved 614844
Nephronophthisis 15, (NPHP15) approved 614845
Nephronophthisis 16, (NPHP16) approved 615382
Nephronophthisis 18, (NPHP 18) approved 615862
Nephronophthisis 19, (NPHP 19) approved 616217
Nephronophthisis 2, (NPHP2) approved 602088