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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgtm@hfea.gov.uk.

Download full approved condition list.

Condition name Status OMIM number Documents
Mitochondrial DNA Depletion Syndrome 9 (MTDPS9) approved 245400
Mitochondrial Myopathy and Ataxia (MMYAT) approved OMIM #617675 (autosomal recessive)
Mitochondrial short-chain enoyl-CoA hydratase 1 deficiency (ECHS1D; Leigh syndrome) approved 616277
Mitochondrial Trifunctional Protein Deficiency approved 609015
Molybdenum Cofactor Deficiency Type B (MOCODB) approved 252160
Muckle-Wells Syndrome (MWS) approved 191900
Mucolipidosis type II approved 252500
Mucopolysaccharidosis III (MPS-III) Type A (Sanfilippo syndrome A) approved 252900
Mucopolysaccharidosis III (MPS-III) Type B approved 252920
Mucopolysaccharidosis III (MPS-III) Type C approved 252930
Mucopolysaccharidosis III (MPS-III) Type D approved 252940
Mucopolysaccharidosis IVA approved 253000
Mucopolysaccharidosis Type I (MPS I) approved 607014, 607015, 607016
Mucopolysaccharidosis Type II (Hunter Syndrome) approved 309900
Mucopolysaccharidosis Type VI (MPS VI) (Maroteaux-Lamy Syndrome) approved 253200
Mucopolysaccharidosis, Type VII awaiting approval 253220
Muenke Syndrome (MNKES) approved 602849
Multiple acyl-CoA dehydrogenase deficiency (MADD) (also known as glutaric aciduria type II) approved 231680
Multiple Congenital Anomalies Hypotonia – Seizures Syndrome 1 (MCAHS1) approved 614080
Multiple Congenital Anomalies Hypotonia – Seizures Syndrome 2 (MCAHS2) approved 300868