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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Immunodeficiency 22 (IMD22) approved 615758
Immunodeficiency 23 (IMD23) approved 615816
Immunodeficiency 24 approved 615897
Immunodeficiency 25 (IMD25) approved 610163
Immunodeficiency 26, with or without neurologic abnormalities approved 615966
Immunodeficiency 27A, mycobacteriosis (IMD27A) approved 209950
Immunodeficiency 28, mycobacteriosis (IMD28) approved 614889
Immunodeficiency 31B approved 613796
Immunodeficiency 31C (IMD31C) approved 614162
Immunodeficiency 32B (IMD32B) approved 226990
Immunodeficiency 33 (IMD33) approved 300636
Immunodeficiency 34, mycobacteriosis, X-linked, (IMD34) approved 300645
Immunodeficiency 35 (IMD35) approved 611521
Immunodeficiency 36 (IMD36) approved 616005
Immunodeficiency 37 (IMD37) approved 616098
Immunodeficiency 38 (IMD38) approved 616126
Immunodeficiency 40 approved 616433
Immunodeficiency 41, with lymphoproliferation and autoimmunity (IMD41) approved 606367
Immunodeficiency 42 (IMD42) approved 616622
Immunodeficiency 42 (IMD42) approved 616622