Skip to main content
HFEA wins prestigious award for data dashboard.Our award-winning dashboard gives users the opportunity to explore HFEA data and find statistics on their own areas of interest. Find out more here.

PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
LIG4 Syndrome approved 606593
Lissencephaly 2 (Norman-Roberts type) (LIS-2), approved 257320
Lissencephaly 5 (LIS5) approved 615191
Lissencephaly 6 with Microcephaly (LIS6) approved 616212
Lissencephaly 8 (LIS8) approved 617255
Lissencephaly, 4 (LIS4) approved 614019
Lissencephaly, type 3 approved 611603
Lissencephaly, X-Linked, 2; LISX2 and Hydranencephaly with Abnormal Genitalia approved 300215
Loeys-Dietz syndrome type 4 approved 614816
Loeys-Dietz syndrome types 1 and 2 approved 609192, 610168
Long Chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency (LCHAD) approved 609016
Long QT Syndrome Types 1, 2, 3, 5 & 6 approved 192500, 613688, 603830, 613695, 613693
Lowe Oculocerebrorenal Syndrome approved 309000
Lymphatic malformation 1, (LMPHM1) (Milroy Syndrome) approved 153100
Lymphatic Malformation 10; LMPHM10 approved 619369
Lymphatic Malformation 11; LMPHM11 approved 619401
Lymphatic Malformation 12; LMPHM12 approved 620014
Lymphatic malformation 3, (LMPHM3) approved 613480
Lymphatic malformation 4, (LMPHM4) approved 615907
Lymphatic malformation 6, (LMPHM6) approved 616843