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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact

Download full approved condition list.

Condition name Status OMIM number Documents
Simpson-Golabi-Behmel Syndrome Type 2 approved 300209
Simpson-Golabi-Behmel Syndrome, Type 1; SGBS1 awaiting approval 312870
Sjogren Larsson Syndrome (SLS) approved 270200
Small-fibre neuropathy (SFN) approved 133020
Smith Lemli Opitz Syndrome (SLOS) approved 270400
SOPH Syndrome (Short Stature, Optic Nerve Atrophy, Pelger-Huet anomaly) approved 614800
Sorsby Fundus Dystrophy; SFD awaiting approval 136900
Sotos syndrome 1 approved 117550
Spastic Ataxia 1, Autosomal Dominant (SPAX1) approved 108600
Spastic Ataxia 2, Autosomal Recessive (SPAX2) approved 611302
Spastic Ataxia 3, Autosomal Recessive (SPAX3) approved 611390
Spastic Ataxia 5, Autosomal Recessive (SPAX5) approved 614487
Spastic Ataxia 8, Autosomal REcessive with Hypo-Myelinating Leukodystrophy (SPAX8) approved 617560
Spastic Ataxia, Charlevoix-Saguenay (SACS) approved 270550
Spastic paraplegia approved
Spastic Paraplegia and Psychomotor Retardation with or without Seizures; SPPRS awaiting approval 616756
Spinal and Bulbar Muscular Atrophy X-linked (Kennedy disease) (in affected male embryos) approved 313200
Spinal Muscular Atrophy 1 (SMA1) approved 253300
Spinal Muscular Atrophy and Respiratory Distress (SMARD1) approved 604320
Spinal muscular atrophy type 2 approved 253550