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The HFEA has launched its new data dashboard with data going back over 30 years. Access it here.

PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Cardiomyopathy, Dilated, with Woolly Hair and Keratoderma (DCWHK) approved 605676
Cardiomyopathy, Dilated, with Woolly Hair, Keratoderma, and Tooth Agenesis (DCWHKTA) approved 615821
Cardiomyopathy, dilated1MM/LVNC10 approved 615396
Cardiomyopathy, Familial Hypertrophic, 26 (CMH26) approved 617047
Cardiomyopathy, Familial Restrictive, 5 (RCM5) approved 617047
Carney Complex approved 160980
Carnitine Acylcarnitine Translocase Deficiency (CACT) approved 212138
Carpenter Syndrome 1 approved 201000
Carpenter Syndrome 2 approved 614976
Cartilage-Hair Hypoplasia approved 250250
Cartilage-hair hypoplasia spectrum approved 157660
Cataract 1 (CTRCT1) approved 116200
Cataract 2 (CTRCT2) approved 604307
Cataract 4 (CTRCT4) approved 115700
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT1) approved 604772
Catecholaminergic Polymorphic Ventricular Tachycardia type 3 (CPVT3) approved 614021
Catecholaminergic Polymorphic Ventricular Tachycardia type 4 (CPVT4) approved 614916
Catecholaminergic Polymorphic Ventricular Tachycardia type 5 with or without muscle weakness (CPVT5) approved 615441
Catecholaminergic Polymorphic Ventricular Tachychardia 2 (CPVT2) approved 611938
Central Core Disease of Muscle (CCD) approved 117000