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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Ichthyosis, cyclic, with epidermolytic hyperkeratosis (ICEHK) approved 607602
Ichthyosis, Spastic Quadriplegia, and Impaired Intellectual Development (ISQMR) approved 614457
Ichythosis hystrix of Curth-Macklin approved 146590
Idiopathic Arterial Calcification of Infancy approved 208000
Immune dysregulation with autoimmunity immunodeficiency, and lymphoproliferation (IDAIL) approved 616100
Immunodeficiency 10 (IMD10) approved 612783
Immunodeficiency 11A (IMD11A) approved 615206
Immunodeficiency 12 (IMD12) approved 615468
Immunodeficiency 14 (IMD14) approved 615513
Immunodeficiency 15B (IMD15B) approved 615592
Immunodeficiency 17, CD3 gamma deficient approved 615607
Immunodeficiency 18 (IMD18) approved 615615
Immunodeficiency 18, SCID variant approved 615615
Immunodeficiency 19 approved 615617
Immunodeficiency 20 (IMD20) approved 615707
Immunodeficiency 21 approved 614172
Immunodeficiency 22 (IMD22) approved 615758
Immunodeficiency 23 (IMD23) approved 615816
Immunodeficiency 24 approved 615897
Immunodeficiency 25 (IMD25) approved 610163