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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Immunodeficiency 35 (IMD35) approved 611521
Immunodeficiency 36 (IMD36) approved 616005
Immunodeficiency 37 (IMD37) approved 616098
Immunodeficiency 38 (IMD38) approved 616126
Immunodeficiency 40 approved 616433
Immunodeficiency 41, with lymphoproliferation and autoimmunity (IMD41) approved 606367
Immunodeficiency 42 (IMD42) approved 616622
Immunodeficiency 42 (IMD42) approved 616622
Immunodeficiency 43 (IMD43) approved 241600
Immunodeficiency 44 (IMD 44) approved 616636
Immunodeficiency 46 (IMD46) approved 616740
Immunodeficiency 47 (IMD47) approved 300972
Immunodeficiency 48 (IMD48) approved 269840
Immunodeficiency 49 (IMD49) approved 617237
Immunodeficiency 50 (IMD50) approved 300988
Immunodeficiency 51 (IMD51) approved 613953
Immunodeficiency 52 (IMD52) approved 617514
Immunodeficiency 54 (IMD54) approved 609981
Immunodeficiency 55 (IMD55) approved 617827
Immunodeficiency 56 (IMD56) approved 615207