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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Amyotrophic lateral sclerosis 23 approved 617839
Amyotrophic lateral sclerosis 4, juvenile approved 602433
Amyotrophic lateral sclerosis 5, juvenile approved 602099
Amyotrophic lateral sclerosis 8 approved 608627
Amyotrophic lateral sclerosis 9 approved 611895
Amyotrophic Lateral Sclerosis Frontotemporal Dementia approved 105550
Anauxetic Dysplasia approved 607095
Andersen Cardiodysrhythmic Periodic Paralysis approved 170390
Anderson Fabry Disease approved 301500
Androgen Insensitivity Syndrome approved 300068
Angelman Syndrome (UBE3A gene only) approved 105830
Aniridia approved 106210
Antithrombin III Deficiency (AT3D) approved 613118
Apert syndrome, OMIM approved 101200
Aplastic anaemia - severe* approved
Argininosuccinic Aciduria approved 207900
Arrhythmogenic Right Ventricular Cardiomyopathy 15 (ARVC15) approved 617047
Arrhythmogenic Right Ventricular Cardiomyopathy/ Dysplasia (ARVC/D), Autosomal Dominant approved
Arrhythmogenic Right Ventricular Dysplasia, Familial, 15 (ARVD15) approved 617047
Arterial Tortuosity Syndrome approved 208050