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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Immunodeficiency 52 (IMD52) approved 617514
Immunodeficiency 54 (IMD54) approved 609981
Immunodeficiency 55 (IMD55) approved 617827
Immunodeficiency 56 (IMD56) approved 615207
Immunodeficiency 57 (IMD57) approved 618108
immunodeficiency 58 (IMD58) approved 618131
Immunodeficiency 63 with lymphoproliferation and autoimmunity (IMD63) approved 618495
Immunodeficiency 64 (IMD64) approved 618534
Immunodeficiency 8 (IMD8) approved 615401
Immunodeficiency 9 approved 612782
Immunodeficiency, common variable, 1, with autoimmunity (CVID1) approved 607594
Immunodeficiency, common variable, 10, with autoimmunity (CVID10) approved 615577
Immunodeficiency, common variable, 12, with autoimmunity (CVID12) approved 616576
Immunodeficiency, common variable, 13, with autoimmunity (CVID13) approved 616873
Immunodeficiency, common variable, 2, with autoimmunity (CVD2) (autosomal recessive form only) approved 240500
Immunodeficiency, common variable, 3, with autoimmunity (CVID3) approved 613493
Immunodeficiency, common variable, 8, with autoimmunity (CVID8) approved 614700
Inclusion Body Myopathy with early onset Paget Disease and Frontotemporal Dementia 1 (IBMPFD1) approved 167320
Incontinentia Pigmenti (IP) approved 308300
Indifference to Pain, Congenital, Autosomal Recessive; CIP approved 243000