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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Haemophilia B (HEMB) approved 306900
Hajdu-Cheney Syndrome (HJCYS) approved 102500
Harel-Yoon Syndrome, (HAYOS) approved 617183
Heimler Syndrome 1 approved 234580
Heimler Syndrome 2 approved 616617
Hennekam Lymphangiectasia-Lymphedema Syndrome 1; HKLLS1 approved 235510
Hennekam Lymphangiectasia-Lymphedema Syndrome 2; HKLLS2 approved 616006
Hennekam Lymphangiectasia-Lymphedema Syndrome 3; HKLLS3 approved 618154
Hereditary Angioedema (HAE) Type I & Type II approved 106100
Hereditary Angioedema (HAE) Type III approved 610618
Hereditary diffuse gastric cancer (HDGC) approved 137215
Hereditary Emberger Syndrome approved 614038
Hereditary Haemorrhagic Telangiectasia (HTT) or Rendu-Osler-Weber Syndrome approved 187300
Hereditary Haemorrhagic Telangiectasia Type 2 (HHT2) approved 600376
Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) approved 150800
Hereditary motor and sensory neuropathy, type IIc (HMSN2C) approved 606071
Hereditary motor and sensory neuropathy, type IIC (HMSN2C) approved 606071
Hereditary Multiple Exostoses Type II approved 133701
Hereditary Nonpolyposis Colorectal Cancer: Lynch Syndrome (for all subtypes) approved
Hereditary Pancreatitis approved 167800