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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Brooke-Spiegler Syndrome (BSS) approved 605041
Brugada Syndrome 1 (Sudden Unexplained Nocturnal Death Syndrome (SUNDS)) approved 601144
Calpainopathy approved 253600
Campomelic Dysplasia approved 114290
Canavan Disease approved 271900
Cantu Syndrome, Hypertrichotic Osteochondrodysplasia approved 239850
Capillary Malformation-Arteriovenous Malformation Type 1 (CM-AVM1) approved 608354
Capillary Malformation-Arteriovenous Malformation Type 2 (CM-AVM2) approved 618196
Cardiomyopathy, dilated 1AA, with or without LVNC approved 612158
Cardiomyopathy, dilated 1BB approved 612877
Cardiomyopathy, dilated 1CC approved 613122
Cardiomyopathy, dilated 1DD approved 613172
Cardiomyopathy, dilated 1E approved 601154
Cardiomyopathy, dilated 1FF approved 613286
Cardiomyopathy, dilated 1I approved 604765
Cardiomyopathy, dilated 1R/LVNC4 approved 613424
Cardiomyopathy, dilated 1W approved 611407
Cardiomyopathy, dilated 1Z approved 611879
Cardiomyopathy, dilated 2A approved 611880
Cardiomyopathy, dilated 3B approved 302045