PGT-M conditions
The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.
When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.
If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.
Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.
Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.
| Condition name | Status | OMIM number | Documents |
|---|---|---|---|
| Inflammatory Bowel Disease 25, Autosomal Recessive (IBD25) | approved | 612567 | |
| Inflammatory Bowel Disease 28, Autosomal Recessive (IBD28)) | approved | 613148 | |
| Insensitivity to Pain, Congenital, with Anhidrosis; CIPA | approved | 256800 | |
| Intellectual Developmental Disorder with or without Peripheral Neuropathy (IDDPN) | awaiting consideration | 619844 | |
| Intellectual Developmental Disorder, Autosomal Dominant 26 (MRD26) | approved | 615834 | |
| Intellectual Developmental Disorder, Autosomal Dominant 29 (MRD29) | approved | 616078 | |
| Intellectual Developmental Disorder, Autosomal Dominant 30, with Speech Delay and Behavioral Abnormalities (MRD30) | approved | 616083 | |
| Intellectual Developmental Disorder, Autosomal Recessive 65 (MRT65) | approved | 618109 | |
| Intellectual Developmental Disorder, X-Linked 1 (XLID1) | approved | 309530 | |
| Intellectual Developmental Disorder, X-Linked 29 (XLID29) | approved | 300419 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic 13 (MRXS13) | approved | 300055 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic 14 (MRXS14) | approved | 300676 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic 33 (MRXS33) | approved | 300966 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic 34 (MRXS34) | approved | 300967 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic, 35 (MRXS35) | approved | 300998 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic, Armfield Type (MRXSA) | approved | 300261 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic, Billuart Type (MRXSBL) | approved | 300486 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic, Cabezas Type (MRXSC) | approved | 300354 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic, Claes-Jensen Type (MRXSCJ) | approved | 300534 | |
| Intellectual Developmental Disorder, X-Linked, Syndromic, Hackmann-Di Donato Type (MRXSHD) | approved | 301039 | |
