Skip to main content
The HFEA has launched its new Media Centre where you can find the latest news and information from us. Access it here.

PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Dystonia 30; DYT30 approved 619291
Dystonia 31; DYT31 approved 619565
Dystonia 33; DYT33 approved 619687
Dystonia 4, Torsion, Autosomal Dominant; DYT4 approved 128101
Dystonia 6, Torsion; DYT6 approved 602629
Dystonia 9; DYT9 approved 601042
Dystonia, Childhood-Onset, with Optic Atrophy and Basal Ganglia Abnormalities; DYTOABG approved 617282
Ectodermal dysplasia / skin fragility syndrome approved 604536
Ectrodactyly, Ectodermal Dysplasia and Cleft Lip/Palate syndrome 3 (EEC3) approved 604292
Ectrodactyly, Ectodermal Dysplasia, Clefting Syndrome (EEC) approved 129900
Ehlers-Danlos periodontal type 1 (EDSPD1) approved 130080
Ehlers-Danlos periodontal type 2 (EDSPD2) approved 617174
Ehlers-Danlos Syndrome, Kyphoscoliotic, type 1 (EDSKSCL1) approved 225400
Ehlers-Danlos Syndrome, Kyphoscoliotic, type 2 (EDSKSCL2) approved 614557
Ehlers-Danlos Type IV approved 130050
Elastin (ELN)-related Supravalvular Aortic Stenosis approved 185500
Ellis-Van Crevald Syndrome approved 225500
Emery-Dreifuss Muscular Dystrophy (x-linked) (EDMD) (Male embryos only) approved 310300
Emery-Dreifuss muscular dystrophy 4 (EDMD4) approved 612998
Emery-Dreifuss muscular dystrophy 5 (EDMD5) approved 612999