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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Glycogen storage disease IXb (GSD9B) approved 261750
Glycogen storage disease IXc (GSD9C) approved 613027
Glycogen storage disease IXd (GSD9D) approved 300559
Glycogen storage disease type 1B approved 232220
Glycogen Storage Disease Type 3 approved 232400
Glycogen Storage Disease Type 4, (GSD4) approved 232500
Glycogen Storage Disease Type Ia approved 232200
Glycogen storage disease V (GSD5) approved 232600
Glycogen storage disease VI (GSD6) approved 232700
Glycogen storage disease VII (GSD7) approved 232800
Goiter, Multinodular 1, with or without Sertoli-Leydig cell tumours (MNG1) approved 138800
Gonadal mosaicism approved
Gorlin Syndrome approved 109400
Greig Cephalopolysyndactyly (GCPS) approved 175700
GRN-related Frontotemporal Lobar Degeneration with TDP43 inclusions approved 607485
Haemoglobin SC disease approved 141900.0038
Haemophilia A (HEMA) approved 306700
Haemophilia B (HEMB) approved 306900
Hajdu-Cheney Syndrome (HJCYS) approved 102500
Harel-Yoon Syndrome, (HAYOS) approved 617183