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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact

Download full approved condition list.

Condition name Status OMIM number Documents
Adenylosuccinate lyase deficiency (ADSLD) approved 103050
Adrenal Hyperplasia, Congenital, due to Steroid 11-Beta-Hydroxylase Deficiency awaiting approval 202010
Adrenal Insufficiency Congenital, with 46, XY sex reversal, partial or complete approved 613743
Adrenoleukodystrophy (Adrenomyeloneuropathy) (ALD) approved 300100
Adult Syndrome approved 103285
Adult-onset vitelliform macular dystrophy approved 153700
Agammaglobulinaemia (x-linked) approved 300755
Agammaglobulinemia and isolated hormone deficiency approved 307200
Aicardi Goutieres syndrome Types 2, 3, 4, 5 and 6 approved 610181, 610329, 610333, 612952, 615010
Aicardi-Goutieres Syndrome 1 (AGS1) approved 225750
Alagille Syndrome approved 118450
Alexander Disease (ALX) approved 203450
Allan-Herndon-Dudley Syndrome approved 300523
Alpha Thalassaemia/mental retardation Syndrome* (ATRX) approved 301040
Alpha Thalassemia approved 141800
Alpha-1-antitrypsin deficiency approved +107400 (where two Z alleles are inherited)
Alpha-Mannosidosis approved 248500
Alport Syndrome approved 301050
Alport Syndrome approved 203780
Alport Syndrome (Autosomal Dominant) approved 104200