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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Focal Dermal Hypoplasia (FDH) approved 305600
Focal Segmental Glomerulosclerosis 7 (FSGS7) approved 616002
Focal Segmental Glomerulosclerosis Type 1 approved 603278
Focal Segmental Glomerulosclerosis Type 2 approved 603965
Focal Segmental Glomerulosclerosis Type 5 approved 613237
Focal Segmental Glomerulosclerosis Type 6 approved 614131
Focal Segmental Glomerulosclerosis Type 8 approved 615032
Focal Segmental Glomerulosclerosis Type 9 approved 616220
Fontaine Progeroid Syndrome (FPS) approved 612289
Fragile X Syndrome (FRAX) approved 300624
Fragile XE syndrome (FRAXE) approved 309548
Fraser Syndrome approved 219000
Fraser Syndrome 2 (FRASRS2) approved 617666
Fraser Syndrome 3 (FRASRS3) approved 617667
Friedreich Ataxia 1 (FRDA) approved 229300
Frontometaphyseal Dysplasia approved 305620
Frontotemporal Dementia approved 600274
Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 approved 615911
Frontotemporal dementia and/or Amyotrophic lateral sclerosis 3 approved 616437
Frontotemporal dementia and/or Amyotrophic lateral sclerosis 4 approved 616439