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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Dehydrated hereditary stomatocytosis approved 194380
Dentatorubral-Pallidoluysian Atrophy (DRPLA) approved 125370
Dentinogenesis Imperfecta 1 (DGI1) approved 125490
Denys-Drash Syndrome (DDS) approved 194080
Desbuquois Dysplasia 1 (DBQD1) approved 251450
Developmental and Epileptic Encephalopathy (DEE3) approved 609304
Developmental and Epileptic Encephalopathy 12 (DEE12) approved 613722
Developmental and Epileptic Encephalopathy 15 (DEE15) approved 615006
Developmental and Epileptic Encephalopathy 16 (DEE16) approved 615338
Developmental and Epileptic Encephalopathy 18 (DEE18) approved 615476
Developmental and Epileptic Encephalopathy 21 (DEE21) approved 615833
Developmental and Epileptic Encephalopathy 23 (DEE23) approved 615859
Developmental and Epileptic Encephalopathy 25 (DEE25) approved 615905
Developmental and Epileptic Encephalopathy 28 (DEE28) approved 616211
Developmental and Epileptic Encephalopathy 29 (DEE29) approved 616339
Developmental and Epileptic Encephalopathy 34 (DEE34) approved 616645
Developmental and Epileptic Encephalopathy 35 (DEE35) approved 616647
Developmental and Epileptic Encephalopathy 37 (DEE37) approved 616981
Developmental and Epileptic Encephalopathy 38 (DEE38) approved 617020
Developmental and Epileptic Encephalopathy 39 (DEE39) approved 612949