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PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Mitochondrial Complex I Deficiency, Nuclear Type 10 (MC1DN10) approved 618233
Mitochondrial Complex I Deficiency, Nuclear Type 11 (MC1DN11) approved 618234
Mitochondrial Complex I Deficiency, Nuclear type 13 (MC1DN13) approved 618235
Mitochondrial Complex I Deficiency, Nuclear Type 14 (MC1DN14) approved 618236
Mitochondrial Complex I Deficiency, Nuclear Type 15 (MC1DN15) approved 618237
Mitochondrial Complex I Deficiency, Nuclear Type 16 (MC1DN16) approved 618238
Mitochondrial Complex I Deficiency, Nuclear type 17 (MC1DN17) approved 618239
Mitochondrial Complex I Deficiency, Nuclear Type 18 (MC1DN18) approved 618240
Mitochondrial Complex I Deficiency, Nuclear Type 19 (MC1DN19) approved 618241
Mitochondrial Complex I Deficiency, Nuclear Type 2 (MC1DN2) approved 618222
Mitochondrial Complex I Deficiency, Nuclear Type 20 (MC1DN20) approved 611126
Mitochondrial Complex I Deficiency, Nuclear Type 21 (MC1DN21) approved 618242
Mitochondrial Complex I Deficiency, Nuclear Type 22 (MC1DN22) approved 618243
Mitochondrial Complex I Deficiency, Nuclear type 23 (MC1DN23) approved 618244
Mitochondrial Complex I Deficiency, Nuclear Type 24 (MC1DN24) approved 618245
Mitochondrial Complex I Deficiency, Nuclear Type 25 (MC1DN25) approved 618246
Mitochondrial Complex I Deficiency, Nuclear type 26 (MC1DN26) approved 618247
Mitochondrial Complex I Deficiency, Nuclear Type 27 (MC1DN27) approved 618248
Mitochondrial Complex I Deficiency, Nuclear type 28 (MC1DN28) approved 618249
Mitochondrial Complex I Deficiency, Nuclear Type 29 (MC1DN29) approved 618250