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The HFEA has launched its new data dashboard with data going back over 30 years. Access it here.

PGT-M conditions

The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.

When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.

If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.

Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.

Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.

Condition name Status OMIM number Documents
Mitochondrial Complex I Deficiency, Nuclear type 23 (MC1DN23) approved 618244
Mitochondrial Complex I Deficiency, Nuclear Type 24 (MC1DN24) approved 618245
Mitochondrial Complex I Deficiency, Nuclear Type 25 (MC1DN25) approved 618246
Mitochondrial Complex I Deficiency, Nuclear type 26 (MC1DN26) approved 618247
Mitochondrial Complex I Deficiency, Nuclear Type 27 (MC1DN27) approved 618248
Mitochondrial Complex I Deficiency, Nuclear type 28 (MC1DN28) approved 618249
Mitochondrial Complex I Deficiency, Nuclear Type 29 (MC1DN29) approved 618250
Mitochondrial Complex I Deficiency, Nuclear Type 3 (MC1DN3) approved 618224
Mitochondrial Complex I Deficiency, Nuclear Type 31 (MC1DN31) approved 618251
Mitochondrial Complex I Deficiency, Nuclear type 32 (MC1DN32) approved 618252
Mitochondrial Complex I Deficiency, Nuclear type 33 (MC1DN33), approved 618253
Mitochondrial Complex I Deficiency, Nuclear type 34 (MC1DN34) approved 618776
Mitochondrial Complex I Deficiency, Nuclear type 35 (MC1DN35) approved 619003
Mitochondrial Complex I Deficiency, Nuclear type 36 (MC1DN36) approved 619170
Mitochondrial Complex I Deficiency, Nuclear type 37 (MC1DN37) approved 619272
Mitochondrial Complex I Deficiency, Nuclear Type 4 (MC1DN4) approved 618225
Mitochondrial Complex I Deficiency, Nuclear Type 5 (MC1DN5) approved 618226
Mitochondrial Complex I Deficiency, Nuclear Type 6 (MC1DN6) approved 618228
Mitochondrial Complex I Deficiency, Nuclear Type 7 (MC1DN7) approved 618229
Mitochondrial Complex I Deficiency, Nuclear Type 8 (MC1DN8) approved 618230