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PGT-M conditions

This table shows all PGT-M conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgtm@hfea.gov.uk.

Download full approved condition list.

Condition name Status OMIM number Documents
Alpha-1-antitrypsin deficiency approved +107400 (where two Z alleles are inherited)
Alpha-Mannosidosis approved 248500
Alport Syndrome approved 301050
Alport Syndrome approved 203780
Alport Syndrome (Autosomal Dominant) approved 104200
Alstrom Syndrome; ALMS approved 203800
Alzheimer's Disease - early onset approved 104300
Alzheimer's Disease - early onset (Types 3 and 4) approved 607822, 606889
Amyotrophic Lateral Sclerosis (ALS) 6 approved 608030
Amyotrophic Lateral Sclerosis 1 (ALS1) approved 105400
Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia approved 612069
Amyotrophic lateral sclerosis 11 approved 612577
Amyotrophic lateral sclerosis 14, with or without frontotemporal dementia approved 613954
Amyotrophic lateral sclerosis 15, with or without frontotemporal dementia approved 300857
Amyotrophic lateral sclerosis 17 approved 614696
Amyotrophic lateral sclerosis 18 approved 614808
Amyotrophic lateral sclerosis 19 approved 615515
Amyotrophic lateral sclerosis 2, juvenile approved 205100
Amyotrophic lateral sclerosis 21 approved 606070
Amyotrophic lateral sclerosis 22 with or without frontotemporal dementia approved 616208