PGT-M conditions
The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.
When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.
If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.
Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.
Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.
| Condition name | Status | OMIM number | Documents |
|---|---|---|---|
| Cutis Laxa, Autosomal Recessive, Type IIB (ARCL2B) | approved | 612940 | |
| Cutis Laxa, Autosomal Recessive, Type IIC (ARCL2C) | approved | 617402 | |
| Cutis Laxa, autosomal recessive, type IID (ARCL2D) | approved | 617403 | |
| Cutis Laxa, autosomal recessive, type IIIA (ARCL3A) | approved | 219150 | |
| Cutis Laxa, autosomal recessive, type IIIB (ARCL3B) | approved | 614438 | |
| Cystic Fibrosis (CF) | approved | 219700 | |
| Czech Dysplasia, metatarsal type also known as Progressive pseudorheumatoid dysplasia with hypoplastic toes | approved | 609162 | |
| D-bifunctional protein deficiency | approved | 261515 | |
| Danon Disease | approved | 300257 | |
| Darier-White Disease (DAR) | approved | 124200 | |
| Deafness, Autosomal Recessive 77 (DFNB77) | approved | 613079 | |
| Deafness, autosomal dominant 15/52 | awaiting consideration | 602459 | |
| Deafness, Autosomal Recessive 12 (DFNB12) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 601386 | |
| Deafness, Autosomal Recessive 15 (DFNB15) | approved | 601869 | |
| Deafness, Autosomal Recessive 18A (DFNB18A) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 602092 | |
| Deafness, Autosomal Recessive 18B (DFNB18B) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 614945 | |
| Deafness, Autosomal Recessive 1A (DFNB1A) | approved | 220290 | |
| Deafness, Autosomal Recessive 2 (DFNB2) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 600060 | |
| Deafness, Autosomal Recessive 21 (DFNB21) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 603629 | |
| Deafness, Autosomal Recessive 22 (DFNB22) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 607039 | |
