Anemia, congenital, nonspherocytic hemolytic, 1, G6PD deficient
OMIM number: 300908
Comments closing date: 05/09/2025
G6PD deficiency is a congenital inherited condition that it passed through generations. It is more common in males and is usually passed on to male children from their mother, even though she has had no symptoms herself. The mother is described as a carrier of the condition. It can cause certain health problems. The most common signs of this condition are: • Jaundice in newborns (yellowing of the skin and eyes shortly after birth) • Sudden breakdown of red blood cells, especially after eating certain foods (like fava beans) or taking certain medicines (like primaquine, a drug used to treat malaria). When red blood cells break down too quickly, it can cause: • Feeling very tired • Back pain • Anaemia (not having enough red blood cells) • Yellowing of the skin and eyes (jaundice)
Review date: 8 August 2027
