PGT-M conditions
The page below lists all PGT-M conditions currently authorised and awaiting consideration by the HFEA.
When publishing genetic conditions on the authorised list, we aim to be as consistent as possible with the OMIM database. However, many conditions may have several different names and we would recommend searching the list using the OMIM number for the condition as this is less likely to change throughout time.
If a condition does not appear on the list, it does not necessarily mean the condition has specifically not been authorised, it may mean that we have never before received an application from a UK centre to perform PGT-M for this condition and it has therefore never been considered by the HFEA.
Please note that we are always processing new applications to add genetic conditions to the list from UK centres licensed to perform PGT-M. This may mean that some authorised conditions may not be displayed. If you are unsure if a condition has been authorised or not, or would like any further information please contact the PGTM team at pgtm@hfea.gov.uk.
Click here for a downloadable list: approved condition list. Please note that the website page below is updated more regularly and is therefore more accurate than the downloadable list.
| Condition name | Status | OMIM number | Documents |
|---|---|---|---|
| Deafness, Autosomal Recessive 84A (DFNB84A) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 613391 | |
| Deafness, Autosomal Recessive 89 (DFNB89) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 613916 | |
| Deafness, Autosomal Recessive 9 (DFNB9) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 601071 | |
| Deafness, Autosomal Recessive 93 (DFNB93) (due to publishing limitations, we can't provide a link to the relevant minutes - please contact HFEA.Licensing@HFEA.gov.uk if you would like to be sent a copy) | approved | 614899 | |
| Deafness, autosomal recessive, 29 (DFNB29) | approved | 614035 | |
| Deafness, Congenital, with Inner Ear Agenesis, Microtia and Microdontia | approved | 610706 | |
| Dehydrated Hereditary Stomatocytosis 1 with or without Pseudohyperkalemia and/or Perinatal Edema (DHS1) | approved | 194380 | |
| Dementia, Lewy Body (DLB) | approved | 127750 | |
| Dent Disease 1 | awaiting consideration | 300009 | |
| Dentatorubral-Pallidoluysian Atrophy (DRPLA) | approved | 125370 | |
| Dentinogenesis Imperfecta 1 (DGI1) | approved | 125490 | |
| Denys-Drash Syndrome (DDS) | approved | 194080 | |
| Desbuquois Dysplasia 1 (DBQD1) | approved | 251450 | |
| Developmental and Epileptic Encephalopathy 57 (DEE57) | approved | 617771 | |
| Developmental and Epileptic Encephalopathy 1 (DEE1) | approved | 308350 | |
| Developmental and Epileptic Encephalopathy 105 with Hypopituitarism (DEE105) | approved | 619983 | |
| Developmental and Epileptic Encephalopathy 106 (DEE106) | approved | 620028 | |
| Developmental and Epileptic Encephalopathy 107 (DEE107) | approved | 620033 | |
| Developmental and Epileptic Encephalopathy 11 (DEE11) | approved | 613721 | |
| Developmental and Epileptic Encephalopathy 111 (DEE111) | approved | 620504 | |
