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PGD conditions

This table shows all PGD conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgd@hfea.gov.uk.

Condition name Status OMIM number Documents
Mitochondrial DNA Depletion Syndrome 7 (MTDPS7) approved 271245
Mitochondrial DNA Depletion Syndrome 8A (MTDPS8A) approved 612075
Mitochondrial DNA Depletion Syndrome 9 (MTDPS9) approved 245400
Mitochondrial Myopathy and Ataxia (MMYAT) approved OMIM #617675 (autosomal recessive)
Mitochondrial short-chain enoyl-CoA hydratase 1 deficiency (ECHS1D; Leigh syndrome) approved 616277
Mitochondrial Trifunctional Protein Deficiency approved 609015
Molybdenum Cofactor Deficiency Type B (MOCODB) approved 252160
Muckle-Wells Syndrome (MWS) approved 191900
Mucolipidosis type II approved 252500
Mucopolysaccharidosis III (MPS-III) Type A (Sanfilippo syndrome A) approved 252900
Mucopolysaccharidosis III (MPS-III) Type B approved 252920
Mucopolysaccharidosis III (MPS-III) Type C approved 252930
Mucopolysaccharidosis III (MPS-III) Type D approved 252940
Mucopolysaccharidosis IVA approved 253000
Mucopolysaccharidosis Type I (MPS I) approved 607014, 607015, 607016
Mucopolysaccharidosis Type II (Hunter Syndrome) approved 309900
Mucopolysaccharidosis Type VI (MPS VI) (Maroteaux-Lamy Syndrome) approved 253200
Muenke Syndrome (MNKES) approved 602849
Multiple acyl-CoA dehydrogenase deficiency (MADD) (also known as glutaric aciduria type II) approved 231680
Multiple Congenital Anomalies Hypotonia – Seizures Syndrome 1 (MCAHS1) approved 614080