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PGD conditions

This table shows all PGD conditions currently approved and awaiting consideration by the HFEA.

Please note that we are updating this database, and some approved conditions may not be displayed. If you are unsure if a condition has been approved or not, please contact pgd@hfea.gov.uk.

Condition name Status OMIM number Documents
MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like episodes) approved 540000
Melnick Needles Syndrome approved 309350
Menkes disease approved 309400
Mental Retardation, autosomal recessive 65 approved 618109
Mental Retardation, X-linked, Syndromic 34, caused by NONO gene mutation (MRXS34) approved 300967
Mental Retardation, X-linked, syndromic, Claes-Jensen type (MRXSCJ) approved 300534
Merosin Deficient Congenital Muscular Dystrophy type 1A (MDC1A) (also known as LAMA2-related Muscular Dystrophy) approved 607855
Metabolic Crises, Recurrent, with Rhabdomyolysis, Cardiac Arrhythmias, and Neurodegeneration (MECRCN) approved 616878
Metachromatic Leukodystrophy (MLD) approved 250100
Metaphyseal Dysplasia without Hypotrichosis approved 250460
Methylmalonic Acidemia (MMA) approved 251000
Methylmalonic Acidemia cb1A approved 251100
Methylmalonic Acidemia cb1B approved 251110
Methylmalonic Aciduria and Homocystinuria approved 277400
Micro Syndrome (WARBM) approved 600118
Microcephalic Osteodysplastic Primordial Dwarfism Type 1, (MOPD1) approved 210710
Microcephalic Osteodysplastic Primordial Dwarfism Type 2, (MOPD2) approved 210720
Microcephaly with or without chorioretinopathy, lymphoedema or mental retardation approved 152950
Microcephaly, developmental delay and seizures, associated with homozygous mutations in the CSTB awaiting approval 601145
Microcephaly, Short Stature and Polymicrogyria with or without seizures (MSSP) approved 614833