Review of scientific methods to avoid mitochondrial disease 2013
In December 2012, the Secretary of State for Health asked the HFEA to provide an updated view of the science to support the assessment of the efficacy and safety of the two mitochondria replacement techniques: pro-nuclear transfer and maternal spindle transfer. The HFEA reconvened the core panel which reported on its updated advice in March 2013. This report was submitted to the Department of Health alongside the advice regarding the public consultation findings, following discussion at an open Authority meeting on 20 March.
- Mitochondrial review - 2013 call for evidence (PDF 169kB)
- Scientific review of the safety and efficacy of methods to avoid mitochondrial disease through assisted conception: update (PDF 170kB)
- Non-confidential minutes of the panel’s 2013 discussions - part 1 (PDF 286kB)
- Non-confidential minutes of the panel’s 2013 discussions - part 2 (PDF 317kB)
Membership of reconvened core panel:
- Professor Neva Haites (chair), University of Aberdeen
- Professor Peter Braude, King’s College London
- Dr Paul De Sousa, University of Edinburgh
- Professor Robin Lovell-Badge, Medical Research Council National Institute for Medical Research
- Professor Anneke Lucassen, University of Southampton and formerly Human Genetics Commission
Terms of reference
The group collated and summarised the current state of expert understanding on the safety and efficacy of maternal spindle transfer and pro-nuclear transfer to update their report of April 2011.
Page last updated: 30 November 2016