• Your treatment options
  • In vitro fertilisation (IVF)
  • Intra-cytoplasmic sperm injection (ICSI)
  • Intrauterine insemination (IUI)
  • Donor insemination (DI)
  • Genetic testing
    • Pre-implantation genetic diagnosis (PGD)
      • PGD conditions licensed by the HFEA
      • Genetic conditions awaiting consideration
      • Sex selection
    • Pre-implantation genetic screening (PGS)
    • Pre-implantation tissue typing
  • Gamete intra fallopian transfer (GIFT)
  • In vitro maturation (IVM)
  • Reproductive immunology
  • Surrogacy
  • Fertility drugs
  • Surgery
• Your storage options
• Using donated sperm, eggs or embryos in your treatment
• When treatment fails, what next?
• Risks of fertility treatment

Preimplantation genetic diagnosis (PGD) is a technique that enables people with a specific inherited condition in their family to avoid passing it on to their children. It involves checking the genes of embryos created through IVF for this genetic condition.

 

If a clinic wishes to use Preimplantation genetic diagnosis (PGD) to test for a new genetic condition, then it must apply to the HFEA for permission. 

 

• What is Preimplantation genetic diagnosis?
• PGD conditions licensed by the HFEA

The following conditions are those which the HFEA is considering to allow clinics to use PGD to test for:

 

Genetic condition	OMIM number*	Date of consideration by Licence Committee
Acute intermittent porphyria (AIP)	176000	25 February
Osteogenesis imperfecta type III	259420	25 February
Niemann pick disease type A	257200	25 February
Ullrich muscular dystrophy	254090	25 February
SMARD1- spinal muscular atrophy and respiratory distress	604320	25 February
5 alpha reductase deficiency	264600	25 February
LCHAD ( long chain 3-hydroxyacyl-CoA dehydrogenase deficiency)	609016	25 February
Muscle eye brain disease	253280	25 February
Paragangliomas 4 (Pgl 4)	115310	25 February
Popliteal ptergyium syndrome	119500	25 February
Succinic semialdehyde dehydrogenase deficiency	271980	25 February
Acute recurrent autosomal recessive rhabdomyolysis and myoglobinuria	268200	25 March
Osteopetrosis, Autosomal recessive 5	259720	25 March
Acute recurrent autosomal recessive rhabdomyolysis and myoglobinuria	268200	25 March
Beta-thalassaemia (Thalassaemia major)	141900	tba
Central core myopathy	117000	tba
Cerebral caverous malformations	116860	tba
Hypophosphatemic rickets: X-linked dominant (Xlh)	307800	tba
Non-classical congenital adrenal hyperplasia (CAH)	201910	tba
Stuve-Wiedemann Syndrome	601559	tba
Branchio oto renal syndrome (BOR Syndrome)	113650	tba
Autosomal dominant polycystic kidney disease	173900	tba

 *what is an OMIM number?

Page last updated: 07 December 2009

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