Centre for Stem Cell Biology, University of Sheffield
Development of human embryonic stem cell lines to Good Manufacturing Practice for treatment of degenerative diseases and conditions (R0115)
Licence Holder: Professor Harry Moore
Human embryonic stem cells are what are called pluripotent and have the capacity to form all cells of the body. There is great potential in the use of these cells to treat major degenerative diseases such as heart disease, diabetes, Parkinson’s disease and some forms of cancer. However, much research and development is required before cell therapies with embryonic stem cells come to fruition.
The Centre of Stem Cell Biology has been established at the University of Sheffield, to investigate the biology and applications of human embryonic stem cells. In this project we will take embryos surplus to clinical need, and donated for the study under fully informed patient consent, to derive new embryonic stem cell lines.
More than one cell line is required because they vary in developmental capacity and may generate different cell types. Eventually cell lines will be produced under the highest possible standards and stringency (good manufacturing/medical protocols) so that they can be used for clinical trials on patients and ultimately for effective cell therapies.
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Page last updated: 11 April 2009
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